C-Terminal lactamization of peptides

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Standard

C-Terminal lactamization of peptides. / Fischer, Niklas H.; Nielsen, Daniel S.; Palmer, Daniel; Meldal, Morten; Diness, Frederik.

I: Chemical Communications, Bind 57, Nr. 7, 2021, s. 895-898.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Fischer, NH, Nielsen, DS, Palmer, D, Meldal, M & Diness, F 2021, 'C-Terminal lactamization of peptides', Chemical Communications, bind 57, nr. 7, s. 895-898. https://doi.org/10.1039/D0CC06018F

APA

Fischer, N. H., Nielsen, D. S., Palmer, D., Meldal, M., & Diness, F. (2021). C-Terminal lactamization of peptides. Chemical Communications, 57(7), 895-898. https://doi.org/10.1039/D0CC06018F

Vancouver

Fischer NH, Nielsen DS, Palmer D, Meldal M, Diness F. C-Terminal lactamization of peptides. Chemical Communications. 2021;57(7):895-898. https://doi.org/10.1039/D0CC06018F

Author

Fischer, Niklas H. ; Nielsen, Daniel S. ; Palmer, Daniel ; Meldal, Morten ; Diness, Frederik. / C-Terminal lactamization of peptides. I: Chemical Communications. 2021 ; Bind 57, Nr. 7. s. 895-898.

Bibtex

@article{ef291b0058c64feab9babd9bfc3c4835,
title = "C-Terminal lactamization of peptides",
abstract = "Solid-phase synthesis of peptides (SPPS) with release through formation of C-terminal γ-, δ-, or ε-lactams is presented. The natural products ciliatamide A and C were synthesized in up to 90% yield. Peptides carrying C-terminal lactams were shown to possess increased bio-stability and comparable biological activity as compared to the parent non-lactamized peptide amides.",
author = "Fischer, {Niklas H.} and Nielsen, {Daniel S.} and Daniel Palmer and Morten Meldal and Frederik Diness",
year = "2021",
doi = "10.1039/D0CC06018F",
language = "English",
volume = "57",
pages = "895--898",
journal = "Chemical Communications",
issn = "1359-7345",
publisher = "Royal Society of Chemistry",
number = "7",

}

RIS

TY - JOUR

T1 - C-Terminal lactamization of peptides

AU - Fischer, Niklas H.

AU - Nielsen, Daniel S.

AU - Palmer, Daniel

AU - Meldal, Morten

AU - Diness, Frederik

PY - 2021

Y1 - 2021

N2 - Solid-phase synthesis of peptides (SPPS) with release through formation of C-terminal γ-, δ-, or ε-lactams is presented. The natural products ciliatamide A and C were synthesized in up to 90% yield. Peptides carrying C-terminal lactams were shown to possess increased bio-stability and comparable biological activity as compared to the parent non-lactamized peptide amides.

AB - Solid-phase synthesis of peptides (SPPS) with release through formation of C-terminal γ-, δ-, or ε-lactams is presented. The natural products ciliatamide A and C were synthesized in up to 90% yield. Peptides carrying C-terminal lactams were shown to possess increased bio-stability and comparable biological activity as compared to the parent non-lactamized peptide amides.

U2 - 10.1039/D0CC06018F

DO - 10.1039/D0CC06018F

M3 - Journal article

VL - 57

SP - 895

EP - 898

JO - Chemical Communications

JF - Chemical Communications

SN - 1359-7345

IS - 7

ER -

ID: 261160414