Trihydroxytrioxatriangulene - An Extended Fluorescein and a Ratiometric pH Sensor

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Fluorescein ver. 2.0: A new, highly fluorescent, pH-sensitive trihydroxytrioxatriangulenium dye (H-TOTA) has been synthesised and characterised. The dye is closely related to fluorescein and may be considered to be a two-dimensional extended version. This new dye can exist in four different protonation states (see graphic) depending on the pH, and its use as a sensitive fluorescent ratiometric pH probe in a physiological buffer is demonstrated.
TidsskriftChemistry: A European Journal
Udgave nummer10
Sider (fra-til)2992 - 2996
Antal sider4
StatusUdgivet - 9 feb. 2010

ID: 19205323