Structure determined charge transport in single DNA molecule break junctions

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Structure determined charge transport in single DNA molecule break junctions. / Wang, Kun; Hamill, Joseph M.; Wang, Bin; Guo, Cunlan; Jiang, Sibo; Huang, Zhen; Xu, Bingqian.

I: Chemical Science, Bind 5, Nr. 9, 09.2014, s. 3425-3431.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Wang, K, Hamill, JM, Wang, B, Guo, C, Jiang, S, Huang, Z & Xu, B 2014, 'Structure determined charge transport in single DNA molecule break junctions', Chemical Science, bind 5, nr. 9, s. 3425-3431. https://doi.org/10.1039/c4sc00888j

APA

Wang, K., Hamill, J. M., Wang, B., Guo, C., Jiang, S., Huang, Z., & Xu, B. (2014). Structure determined charge transport in single DNA molecule break junctions. Chemical Science, 5(9), 3425-3431. https://doi.org/10.1039/c4sc00888j

Vancouver

Wang K, Hamill JM, Wang B, Guo C, Jiang S, Huang Z o.a. Structure determined charge transport in single DNA molecule break junctions. Chemical Science. 2014 sep.;5(9):3425-3431. https://doi.org/10.1039/c4sc00888j

Author

Wang, Kun ; Hamill, Joseph M. ; Wang, Bin ; Guo, Cunlan ; Jiang, Sibo ; Huang, Zhen ; Xu, Bingqian. / Structure determined charge transport in single DNA molecule break junctions. I: Chemical Science. 2014 ; Bind 5, Nr. 9. s. 3425-3431.

Bibtex

@article{e868cdc08cfd42ea915ce318945b9247,
title = "Structure determined charge transport in single DNA molecule break junctions",
abstract = "Experimental study of the charge transport properties associated with structural variations due to a change in the ionic environment will provide essential physical information in determining the nature of DNA molecules. This work reports an experimental study of the change in electronic transport properties induced by the conformational transition of a poly d(GC)4 DNA. By gradually increasing the concentration of MgCl2 in the buffer solution from 0 M to 4 M, the conductance of the single DNA molecule decreased by two orders of magnitude. Circular dichroism (CD) measurements confirmed that a B to Z conformational transition caused the reduction in conductance. Using a stretch-hold mode scanning probe microscopy break junction (SPMBJ) technique, this B-Z transition process was monitored and a transition trend line was successfully achieved from conductance measurements alone. The transition midpoint occurred at a MgCl2 concentration of 0.93 M for this DNA sequence. This method provides a general tool to study transitions of molecular properties associated with conductance differences.",
author = "Kun Wang and Hamill, {Joseph M.} and Bin Wang and Cunlan Guo and Sibo Jiang and Zhen Huang and Bingqian Xu",
year = "2014",
month = sep,
doi = "10.1039/c4sc00888j",
language = "English",
volume = "5",
pages = "3425--3431",
journal = "Chemical Science",
issn = "2041-6520",
publisher = "Royal Society of Chemistry",
number = "9",

}

RIS

TY - JOUR

T1 - Structure determined charge transport in single DNA molecule break junctions

AU - Wang, Kun

AU - Hamill, Joseph M.

AU - Wang, Bin

AU - Guo, Cunlan

AU - Jiang, Sibo

AU - Huang, Zhen

AU - Xu, Bingqian

PY - 2014/9

Y1 - 2014/9

N2 - Experimental study of the charge transport properties associated with structural variations due to a change in the ionic environment will provide essential physical information in determining the nature of DNA molecules. This work reports an experimental study of the change in electronic transport properties induced by the conformational transition of a poly d(GC)4 DNA. By gradually increasing the concentration of MgCl2 in the buffer solution from 0 M to 4 M, the conductance of the single DNA molecule decreased by two orders of magnitude. Circular dichroism (CD) measurements confirmed that a B to Z conformational transition caused the reduction in conductance. Using a stretch-hold mode scanning probe microscopy break junction (SPMBJ) technique, this B-Z transition process was monitored and a transition trend line was successfully achieved from conductance measurements alone. The transition midpoint occurred at a MgCl2 concentration of 0.93 M for this DNA sequence. This method provides a general tool to study transitions of molecular properties associated with conductance differences.

AB - Experimental study of the charge transport properties associated with structural variations due to a change in the ionic environment will provide essential physical information in determining the nature of DNA molecules. This work reports an experimental study of the change in electronic transport properties induced by the conformational transition of a poly d(GC)4 DNA. By gradually increasing the concentration of MgCl2 in the buffer solution from 0 M to 4 M, the conductance of the single DNA molecule decreased by two orders of magnitude. Circular dichroism (CD) measurements confirmed that a B to Z conformational transition caused the reduction in conductance. Using a stretch-hold mode scanning probe microscopy break junction (SPMBJ) technique, this B-Z transition process was monitored and a transition trend line was successfully achieved from conductance measurements alone. The transition midpoint occurred at a MgCl2 concentration of 0.93 M for this DNA sequence. This method provides a general tool to study transitions of molecular properties associated with conductance differences.

UR - http://www.scopus.com/inward/record.url?scp=84905190110&partnerID=8YFLogxK

U2 - 10.1039/c4sc00888j

DO - 10.1039/c4sc00888j

M3 - Journal article

AN - SCOPUS:84905190110

VL - 5

SP - 3425

EP - 3431

JO - Chemical Science

JF - Chemical Science

SN - 2041-6520

IS - 9

ER -

ID: 381636947