Catalytic click reactions

Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning › fagfællebedømt

Standard

Catalytic click reactions. / Schoffelen, Sanne; Meldal, Morten.

Applied Homogeneous Catalysis with Organometallic Compounds: A Comprehensive Handbook in Three Volumes. red. / Boy Cornils; Wolfgang A Herrmann; Matthias Beller. Wiley-Blackwell, 2012. s. 1541-1556.

Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning › fagfællebedømt

Harvard

Schoffelen, S & Meldal, M 2012, Catalytic click reactions. i B Cornils, WA Herrmann & M Beller (red), Applied Homogeneous Catalysis with Organometallic Compounds: A Comprehensive Handbook in Three Volumes. Wiley-Blackwell, s. 1541-1556. https://doi.org/10.1002/9783527651733.ch32

APA

Schoffelen, S., & Meldal, M. (2012). Catalytic click reactions. I B. Cornils, W. A. Herrmann, & M. Beller (red.), Applied Homogeneous Catalysis with Organometallic Compounds: A Comprehensive Handbook in Three Volumes (s. 1541-1556). Wiley-Blackwell. https://doi.org/10.1002/9783527651733.ch32

Vancouver

Schoffelen S, Meldal M. Catalytic click reactions. I Cornils B, Herrmann WA, Beller M, red., Applied Homogeneous Catalysis with Organometallic Compounds: A Comprehensive Handbook in Three Volumes. Wiley-Blackwell. 2012. s. 1541-1556 https://doi.org/10.1002/9783527651733.ch32

Author

Schoffelen, Sanne ; Meldal, Morten. / Catalytic click reactions. Applied Homogeneous Catalysis with Organometallic Compounds: A Comprehensive Handbook in Three Volumes. red. / Boy Cornils ; Wolfgang A Herrmann ; Matthias Beller. Wiley-Blackwell, 2012. s. 1541-1556

Bibtex

@inbook{3079fd2fead64bf8b01e1d1e86bed82b,
title = "Catalytic click reactions",
abstract = "This chapter discusses the most well-known click reaction the copper-catalyzed azide-alkyne cycloaddition (CuAAC), as well as ruthenium-catalyzed process (RuAAC). It also discusses a selection of click reactions that are orthogonal to CuAAC and RuAAC. However, these are not necessarily catalytic; they can be used in concert with their catalytic counterparts, allowing for the synthesis of a large variety of complex molecular structures. In CuAAC reactions, ligands protect Cu (I) from disproportionation and oxidation due to the presence of oxygen and other oxidizing species. Ligands may also activate the Cu atom for productive interaction with the alkyne and azide and promote the transition-state complex by substrate binding. Another efficient, transition-metal-mediated click reaction is the versatile Cu (I)-catalyzed nitroxide radical coupling (NRC) with an alkyl halide. Macro-molecular ligands derivatized with 2, 2, 6, 6-tetramethylpiperidine-oxyl (TEMPO) can be coupled with alkyl halides using a Cu bromide-ligand catalyst at elevated temperatures.",
author = "Sanne Schoffelen and Morten Meldal",
year = "2012",
month = jan,
day = "1",
doi = "10.1002/9783527651733.ch32",
language = "English",
isbn = "9783527328970",
pages = "1541--1556",
editor = "Boy Cornils and Herrmann, {Wolfgang A} and Matthias Beller",
booktitle = "Applied Homogeneous Catalysis with Organometallic Compounds",
publisher = "Wiley-Blackwell",
address = "United Kingdom",

}

RIS

TY - CHAP

T1 - Catalytic click reactions

AU - Schoffelen, Sanne

AU - Meldal, Morten

PY - 2012/1/1

Y1 - 2012/1/1

N2 - This chapter discusses the most well-known click reaction the copper-catalyzed azide-alkyne cycloaddition (CuAAC), as well as ruthenium-catalyzed process (RuAAC). It also discusses a selection of click reactions that are orthogonal to CuAAC and RuAAC. However, these are not necessarily catalytic; they can be used in concert with their catalytic counterparts, allowing for the synthesis of a large variety of complex molecular structures. In CuAAC reactions, ligands protect Cu (I) from disproportionation and oxidation due to the presence of oxygen and other oxidizing species. Ligands may also activate the Cu atom for productive interaction with the alkyne and azide and promote the transition-state complex by substrate binding. Another efficient, transition-metal-mediated click reaction is the versatile Cu (I)-catalyzed nitroxide radical coupling (NRC) with an alkyl halide. Macro-molecular ligands derivatized with 2, 2, 6, 6-tetramethylpiperidine-oxyl (TEMPO) can be coupled with alkyl halides using a Cu bromide-ligand catalyst at elevated temperatures.

AB - This chapter discusses the most well-known click reaction the copper-catalyzed azide-alkyne cycloaddition (CuAAC), as well as ruthenium-catalyzed process (RuAAC). It also discusses a selection of click reactions that are orthogonal to CuAAC and RuAAC. However, these are not necessarily catalytic; they can be used in concert with their catalytic counterparts, allowing for the synthesis of a large variety of complex molecular structures. In CuAAC reactions, ligands protect Cu (I) from disproportionation and oxidation due to the presence of oxygen and other oxidizing species. Ligands may also activate the Cu atom for productive interaction with the alkyne and azide and promote the transition-state complex by substrate binding. Another efficient, transition-metal-mediated click reaction is the versatile Cu (I)-catalyzed nitroxide radical coupling (NRC) with an alkyl halide. Macro-molecular ligands derivatized with 2, 2, 6, 6-tetramethylpiperidine-oxyl (TEMPO) can be coupled with alkyl halides using a Cu bromide-ligand catalyst at elevated temperatures.

U2 - 10.1002/9783527651733.ch32

DO - 10.1002/9783527651733.ch32

M3 - Book chapter

AN - SCOPUS:85062759103

SN - 9783527328970

SP - 1541

EP - 1556

BT - Applied Homogeneous Catalysis with Organometallic Compounds

A2 - Cornils, Boy

A2 - Herrmann, Wolfgang A

A2 - Beller, Matthias

PB - Wiley-Blackwell

ER -

ID: 321824517