Dendrimers in biology and nanomedicine

Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning › fagfællebedømt

Standard

Dendrimers in biology and nanomedicine. / Christensen, Jørn Bolstad.

Organic Synthesis and Molecular Engineering. Wiley-Interscience, 2013. s. 361-392.

Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning › fagfællebedømt

Harvard

Christensen, JB 2013, Dendrimers in biology and nanomedicine. i Organic Synthesis and Molecular Engineering. Wiley-Interscience, s. 361-392. https://doi.org/10.1002/9781118736449.ch13

APA

Christensen, J. B. (2013). Dendrimers in biology and nanomedicine. I Organic Synthesis and Molecular Engineering (s. 361-392). Wiley-Interscience. https://doi.org/10.1002/9781118736449.ch13

Vancouver

Christensen JB. Dendrimers in biology and nanomedicine. I Organic Synthesis and Molecular Engineering. Wiley-Interscience. 2013. s. 361-392 https://doi.org/10.1002/9781118736449.ch13

Author

Christensen, Jørn Bolstad. / Dendrimers in biology and nanomedicine. Organic Synthesis and Molecular Engineering. Wiley-Interscience, 2013. s. 361-392

Bibtex

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title = "Dendrimers in biology and nanomedicine",
abstract = "Dendrimers and dendrons are classes of highly branched {"}tree-shaped{"} nanosized molecules. This chapter deals with dendrimers in connection with biology and medicine, and begins with a discussion on their properties. In a divergent approach of synthesis, the dendrimer is essentially synthesized beginning at the core and building outward, whereas in the convergent approach the dendrimer is built starting from the periphery and going toward the core. Polyamidoamine (PAMAM) dendrimers, are synthesized by Michael addition of methylacrylate to polyamines followed by amidation by treatment with an excess of 1,2-ethanediamine. The chapter highlights toxicity of dendrimers, and then goes on to discuss the use of dendrimers in diagnostics and dendrimer-based reagents in imaging. Other topics that are discussed include anti-inflammatory activities of dendrimers, DNA transfection, and small interfering RNA (siRNA).",
keywords = "Biology, Dendrimer-based reagents, Dendrimers, DNA transfection, Nanomedicine, Polyamidoamine (PAMAM) dendrimers, Small interfering RNA (siRNA)",
author = "Christensen, {J{\o}rn Bolstad}",
year = "2013",
month = oct,
day = "25",
doi = "10.1002/9781118736449.ch13",
language = "English",
isbn = "9781118150924",
pages = "361--392",
booktitle = "Organic Synthesis and Molecular Engineering",
publisher = "Wiley-Interscience",

}

RIS

TY - CHAP

T1 - Dendrimers in biology and nanomedicine

AU - Christensen, Jørn Bolstad

PY - 2013/10/25

Y1 - 2013/10/25

N2 - Dendrimers and dendrons are classes of highly branched "tree-shaped" nanosized molecules. This chapter deals with dendrimers in connection with biology and medicine, and begins with a discussion on their properties. In a divergent approach of synthesis, the dendrimer is essentially synthesized beginning at the core and building outward, whereas in the convergent approach the dendrimer is built starting from the periphery and going toward the core. Polyamidoamine (PAMAM) dendrimers, are synthesized by Michael addition of methylacrylate to polyamines followed by amidation by treatment with an excess of 1,2-ethanediamine. The chapter highlights toxicity of dendrimers, and then goes on to discuss the use of dendrimers in diagnostics and dendrimer-based reagents in imaging. Other topics that are discussed include anti-inflammatory activities of dendrimers, DNA transfection, and small interfering RNA (siRNA).

AB - Dendrimers and dendrons are classes of highly branched "tree-shaped" nanosized molecules. This chapter deals with dendrimers in connection with biology and medicine, and begins with a discussion on their properties. In a divergent approach of synthesis, the dendrimer is essentially synthesized beginning at the core and building outward, whereas in the convergent approach the dendrimer is built starting from the periphery and going toward the core. Polyamidoamine (PAMAM) dendrimers, are synthesized by Michael addition of methylacrylate to polyamines followed by amidation by treatment with an excess of 1,2-ethanediamine. The chapter highlights toxicity of dendrimers, and then goes on to discuss the use of dendrimers in diagnostics and dendrimer-based reagents in imaging. Other topics that are discussed include anti-inflammatory activities of dendrimers, DNA transfection, and small interfering RNA (siRNA).

KW - Biology

KW - Dendrimer-based reagents

KW - Dendrimers

KW - DNA transfection

KW - Nanomedicine

KW - Polyamidoamine (PAMAM) dendrimers

KW - Small interfering RNA (siRNA)

U2 - 10.1002/9781118736449.ch13

DO - 10.1002/9781118736449.ch13

M3 - Book chapter

AN - SCOPUS:85016075743

SN - 9781118150924

SP - 361

EP - 392

BT - Organic Synthesis and Molecular Engineering

PB - Wiley-Interscience

ER -

ID: 261046804