Rate constants for the reactions of OH radicals and Cl atoms with CH₃CH₂NO₂, CH₃CH₂CH₂NO₂, CH₃CH₂CH₂CH₂NO₂, and CH₃CH₂CH₂CH₂CH₂NO₂ have been determined at 295±3 K and a total pressure of approximately 1 atm. The OH rate data were obtained using both the absolute rate technique of pulse radiolysis combined with kinetic spectroscopy and a conventional photolytic relative rate method. The Cl rate constants were measured using only the relative rate method. The results are discussed in terms of reactivity trends.