Versatile solid-phase synthesis of peptide-derived 2-oxazolines. Application in the synthesis of ligands for asymmetric catalysis

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Standard

Versatile solid-phase synthesis of peptide-derived 2-oxazolines. Application in the synthesis of ligands for asymmetric catalysis. / Benito, Juan M.; Christensen, Christian A.; Meldal, Morten.

I: Organic Letters, Bind 7, Nr. 4, 17.02.2005, s. 581-584.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Benito, JM, Christensen, CA & Meldal, M 2005, 'Versatile solid-phase synthesis of peptide-derived 2-oxazolines. Application in the synthesis of ligands for asymmetric catalysis', Organic Letters, bind 7, nr. 4, s. 581-584. https://doi.org/10.1021/ol047675h

APA

Benito, J. M., Christensen, C. A., & Meldal, M. (2005). Versatile solid-phase synthesis of peptide-derived 2-oxazolines. Application in the synthesis of ligands for asymmetric catalysis. Organic Letters, 7(4), 581-584. https://doi.org/10.1021/ol047675h

Vancouver

Benito JM, Christensen CA, Meldal M. Versatile solid-phase synthesis of peptide-derived 2-oxazolines. Application in the synthesis of ligands for asymmetric catalysis. Organic Letters. 2005 feb. 17;7(4):581-584. https://doi.org/10.1021/ol047675h

Author

Benito, Juan M. ; Christensen, Christian A. ; Meldal, Morten. / Versatile solid-phase synthesis of peptide-derived 2-oxazolines. Application in the synthesis of ligands for asymmetric catalysis. I: Organic Letters. 2005 ; Bind 7, Nr. 4. s. 581-584.

Bibtex

@article{8109f6792f504acdb5338e5010732a6d,
title = "Versatile solid-phase synthesis of peptide-derived 2-oxazolines. Application in the synthesis of ligands for asymmetric catalysis",
abstract = "(Chemical Equation Presented) A mild and high-yielding procedure for the solid-phase synthesis of 2-oxazolines from amino acids is described. The two-step protocol is based on the iodination of serine containing peptides, followed by in situ nucleophilic attack of the carbonyl oxygen from the next amino acid. Phosphinylation of the terminal amino group cleanly furnishes a resin-bound phosphine-oxazoline ligand, which upon palladium complexation was applied as catalyst in asymmetric allylic substitution.",
author = "Benito, {Juan M.} and Christensen, {Christian A.} and Morten Meldal",
year = "2005",
month = feb,
day = "17",
doi = "10.1021/ol047675h",
language = "English",
volume = "7",
pages = "581--584",
journal = "Organic Letters",
issn = "1523-7060",
publisher = "American Chemical Society",
number = "4",

}

RIS

TY - JOUR

T1 - Versatile solid-phase synthesis of peptide-derived 2-oxazolines. Application in the synthesis of ligands for asymmetric catalysis

AU - Benito, Juan M.

AU - Christensen, Christian A.

AU - Meldal, Morten

PY - 2005/2/17

Y1 - 2005/2/17

N2 - (Chemical Equation Presented) A mild and high-yielding procedure for the solid-phase synthesis of 2-oxazolines from amino acids is described. The two-step protocol is based on the iodination of serine containing peptides, followed by in situ nucleophilic attack of the carbonyl oxygen from the next amino acid. Phosphinylation of the terminal amino group cleanly furnishes a resin-bound phosphine-oxazoline ligand, which upon palladium complexation was applied as catalyst in asymmetric allylic substitution.

AB - (Chemical Equation Presented) A mild and high-yielding procedure for the solid-phase synthesis of 2-oxazolines from amino acids is described. The two-step protocol is based on the iodination of serine containing peptides, followed by in situ nucleophilic attack of the carbonyl oxygen from the next amino acid. Phosphinylation of the terminal amino group cleanly furnishes a resin-bound phosphine-oxazoline ligand, which upon palladium complexation was applied as catalyst in asymmetric allylic substitution.

UR - http://www.scopus.com/inward/record.url?scp=14844357298&partnerID=8YFLogxK

U2 - 10.1021/ol047675h

DO - 10.1021/ol047675h

M3 - Journal article

C2 - 15704899

AN - SCOPUS:14844357298

VL - 7

SP - 581

EP - 584

JO - Organic Letters

JF - Organic Letters

SN - 1523-7060

IS - 4

ER -

ID: 326847627