Photoswitchable inhibitors of human β-glucocerebrosidase

Publikation: Bidrag til tidsskriftLetterForskningfagfællebedømt

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Photoswitchable inhibitors of human β-glucocerebrosidase. / Davighi, Maria Giulia; Clemente, Francesca; Matassini, Camilla; Cardona, Francesca; Nielsen, Mogens Brøndsted; Goti, Andrea; Morrone, Amelia; Paoli, Paolo; Cacciarini, Martina.

I: Organic & Biomolecular Chemistry, Bind 20, Nr. 8, 2022, s. 1637–1641 .

Publikation: Bidrag til tidsskriftLetterForskningfagfællebedømt

Harvard

Davighi, MG, Clemente, F, Matassini, C, Cardona, F, Nielsen, MB, Goti, A, Morrone, A, Paoli, P & Cacciarini, M 2022, 'Photoswitchable inhibitors of human β-glucocerebrosidase', Organic & Biomolecular Chemistry, bind 20, nr. 8, s. 1637–1641 . https://doi.org/10.1039/D1OB02159A

APA

Davighi, M. G., Clemente, F., Matassini, C., Cardona, F., Nielsen, M. B., Goti, A., Morrone, A., Paoli, P., & Cacciarini, M. (2022). Photoswitchable inhibitors of human β-glucocerebrosidase. Organic & Biomolecular Chemistry, 20(8), 1637–1641 . https://doi.org/10.1039/D1OB02159A

Vancouver

Davighi MG, Clemente F, Matassini C, Cardona F, Nielsen MB, Goti A o.a. Photoswitchable inhibitors of human β-glucocerebrosidase. Organic & Biomolecular Chemistry. 2022;20(8):1637–1641 . https://doi.org/10.1039/D1OB02159A

Author

Davighi, Maria Giulia ; Clemente, Francesca ; Matassini, Camilla ; Cardona, Francesca ; Nielsen, Mogens Brøndsted ; Goti, Andrea ; Morrone, Amelia ; Paoli, Paolo ; Cacciarini, Martina. / Photoswitchable inhibitors of human β-glucocerebrosidase. I: Organic & Biomolecular Chemistry. 2022 ; Bind 20, Nr. 8. s. 1637–1641 .

Bibtex

@article{308256872f8042988391d90ab8fc4c8b,
title = "Photoswitchable inhibitors of human β-glucocerebrosidase",
abstract = "Light-switchable inhibitors of the enzyme β-glucocerebrosidase (GCase) have been developed by anchoring a specific azasugar to a dihydroazulene or an azobenzene responsive moiety. Their inhibitory effect towards human GCase, before and after irradiation are reported, and the effect on thermal denaturation of recombinant GCase and cytotoxicity were studied on selected candidates.",
author = "Davighi, {Maria Giulia} and Francesca Clemente and Camilla Matassini and Francesca Cardona and Nielsen, {Mogens Br{\o}ndsted} and Andrea Goti and Amelia Morrone and Paolo Paoli and Martina Cacciarini",
year = "2022",
doi = "10.1039/D1OB02159A",
language = "English",
volume = "20",
pages = "1637–1641 ",
journal = "Organic & Biomolecular Chemistry",
issn = "1470-4358",
publisher = "Royal Society of Chemistry",
number = "8",

}

RIS

TY - JOUR

T1 - Photoswitchable inhibitors of human β-glucocerebrosidase

AU - Davighi, Maria Giulia

AU - Clemente, Francesca

AU - Matassini, Camilla

AU - Cardona, Francesca

AU - Nielsen, Mogens Brøndsted

AU - Goti, Andrea

AU - Morrone, Amelia

AU - Paoli, Paolo

AU - Cacciarini, Martina

PY - 2022

Y1 - 2022

N2 - Light-switchable inhibitors of the enzyme β-glucocerebrosidase (GCase) have been developed by anchoring a specific azasugar to a dihydroazulene or an azobenzene responsive moiety. Their inhibitory effect towards human GCase, before and after irradiation are reported, and the effect on thermal denaturation of recombinant GCase and cytotoxicity were studied on selected candidates.

AB - Light-switchable inhibitors of the enzyme β-glucocerebrosidase (GCase) have been developed by anchoring a specific azasugar to a dihydroazulene or an azobenzene responsive moiety. Their inhibitory effect towards human GCase, before and after irradiation are reported, and the effect on thermal denaturation of recombinant GCase and cytotoxicity were studied on selected candidates.

U2 - 10.1039/D1OB02159A

DO - 10.1039/D1OB02159A

M3 - Letter

VL - 20

SP - 1637

EP - 1641

JO - Organic & Biomolecular Chemistry

JF - Organic & Biomolecular Chemistry

SN - 1470-4358

IS - 8

ER -

ID: 291814538