Silylated Sugars – Synthesis and Properties
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Silicon has been used in carbohydrate chemistry for half a century, but mostly as a protective group for sugar alcohols. Recently, the use of silicon has expanded to functionalization via C–H activation, conformational arming of glycosyl donors, and conformational alteration of carbohydrates. Silicon has proven useful as more than a protective group and during the last one and a half decades we have demonstrated how it influences both the reactivity of glycosyl donors and stereochemical outcome of glycosylations. Silicon can also be attached directly to the sugar C-backbone, which has even more pronounced effects on the chemistry and properties of the molecules. In this Account, we will give a tour through our work involving silicon and carbohydrates.
Originalsprog | Engelsk |
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Tidsskrift | Synlett |
Vol/bind | 33 |
Udgave nummer | 5 |
Sider (fra-til) | 415-428 |
Antal sider | 14 |
ISSN | 0936-5214 |
DOI | |
Status | Udgivet - 2022 |
ID: 285452857