Ultrabright Fluorescent Organic Nanoparticles Based on Small-Molecule Ionic Isolation Lattices**

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Standard

Ultrabright Fluorescent Organic Nanoparticles Based on Small-Molecule Ionic Isolation Lattices**. / Chen, Junsheng; Fateminia, S. M. Ali; Kacenauskaite, Laura; Baerentsen, Nicolai; Gronfeldt Stenspil, Stine; Bredehoeft, Jona; Martinez, Karen L.; Flood, Amar H.; Laursen, Bo W.

I: Angewandte Chemie International Edition, Bind 60, Nr. 17, 19.04.2021, s. 9450-9458.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Chen, J, Fateminia, SMA, Kacenauskaite, L, Baerentsen, N, Gronfeldt Stenspil, S, Bredehoeft, J, Martinez, KL, Flood, AH & Laursen, BW 2021, 'Ultrabright Fluorescent Organic Nanoparticles Based on Small-Molecule Ionic Isolation Lattices**', Angewandte Chemie International Edition, bind 60, nr. 17, s. 9450-9458. https://doi.org/10.1002/anie.202100950

APA

Chen, J., Fateminia, S. M. A., Kacenauskaite, L., Baerentsen, N., Gronfeldt Stenspil, S., Bredehoeft, J., Martinez, K. L., Flood, A. H., & Laursen, B. W. (2021). Ultrabright Fluorescent Organic Nanoparticles Based on Small-Molecule Ionic Isolation Lattices**. Angewandte Chemie International Edition, 60(17), 9450-9458. https://doi.org/10.1002/anie.202100950

Vancouver

Chen J, Fateminia SMA, Kacenauskaite L, Baerentsen N, Gronfeldt Stenspil S, Bredehoeft J o.a. Ultrabright Fluorescent Organic Nanoparticles Based on Small-Molecule Ionic Isolation Lattices**. Angewandte Chemie International Edition. 2021 apr. 19;60(17):9450-9458. https://doi.org/10.1002/anie.202100950

Author

Chen, Junsheng ; Fateminia, S. M. Ali ; Kacenauskaite, Laura ; Baerentsen, Nicolai ; Gronfeldt Stenspil, Stine ; Bredehoeft, Jona ; Martinez, Karen L. ; Flood, Amar H. ; Laursen, Bo W. / Ultrabright Fluorescent Organic Nanoparticles Based on Small-Molecule Ionic Isolation Lattices**. I: Angewandte Chemie International Edition. 2021 ; Bind 60, Nr. 17. s. 9450-9458.

Bibtex

@article{ce073f7f48944d0a9870901d46dba081,
title = "Ultrabright Fluorescent Organic Nanoparticles Based on Small-Molecule Ionic Isolation Lattices**",
abstract = "Ultrabright fluorescent nanoparticles (NPs) hold great promise for demanding bioimaging applications. Recently, extremely bright molecular crystals of cationic fluorophores were obtained by hierarchical coassembly with cyanostar anion-receptor complexes. These small-molecule ionic isolation lattices (SMILES) ensure spatial and electronic isolation to prohibit aggregation quenching of dyes. We report a simple, one-step supramolecular approach to formulate SMILES materials into NPs. Rhodamine-based SMILES NPs stabilized by glycol amphiphiles show high fluorescence quantum yield (30 %) and brightness per volume (5000 M-1 cm(-1)/nm(3)) with 400 dye molecules packed into 16-nm particles, corresponding to a particle absorption coefficient of 4x10(7) M-1 cm(-1). UV excitation of the cyanostar component leads to higher brightness (>6000 M-1 cm(-1)/ nm(3)) by energy transfer to rhodamine emitters. Coated NPs stain cells and are thus promising for bioimaging.",
keywords = "cell imaging, cyanostar macrocycles, fluorescent dyes, fluorescent nanoparticles, SMILES",
author = "Junsheng Chen and Fateminia, {S. M. Ali} and Laura Kacenauskaite and Nicolai Baerentsen and {Gronfeldt Stenspil}, Stine and Jona Bredehoeft and Martinez, {Karen L.} and Flood, {Amar H.} and Laursen, {Bo W.}",
year = "2021",
month = apr,
day = "19",
doi = "10.1002/anie.202100950",
language = "English",
volume = "60",
pages = "9450--9458",
journal = "Angewandte Chemie International Edition",
issn = "1433-7851",
publisher = "Wiley-VCH Verlag GmbH & Co. KGaA",
number = "17",

}

RIS

TY - JOUR

T1 - Ultrabright Fluorescent Organic Nanoparticles Based on Small-Molecule Ionic Isolation Lattices**

AU - Chen, Junsheng

AU - Fateminia, S. M. Ali

AU - Kacenauskaite, Laura

AU - Baerentsen, Nicolai

AU - Gronfeldt Stenspil, Stine

AU - Bredehoeft, Jona

AU - Martinez, Karen L.

AU - Flood, Amar H.

AU - Laursen, Bo W.

PY - 2021/4/19

Y1 - 2021/4/19

N2 - Ultrabright fluorescent nanoparticles (NPs) hold great promise for demanding bioimaging applications. Recently, extremely bright molecular crystals of cationic fluorophores were obtained by hierarchical coassembly with cyanostar anion-receptor complexes. These small-molecule ionic isolation lattices (SMILES) ensure spatial and electronic isolation to prohibit aggregation quenching of dyes. We report a simple, one-step supramolecular approach to formulate SMILES materials into NPs. Rhodamine-based SMILES NPs stabilized by glycol amphiphiles show high fluorescence quantum yield (30 %) and brightness per volume (5000 M-1 cm(-1)/nm(3)) with 400 dye molecules packed into 16-nm particles, corresponding to a particle absorption coefficient of 4x10(7) M-1 cm(-1). UV excitation of the cyanostar component leads to higher brightness (>6000 M-1 cm(-1)/ nm(3)) by energy transfer to rhodamine emitters. Coated NPs stain cells and are thus promising for bioimaging.

AB - Ultrabright fluorescent nanoparticles (NPs) hold great promise for demanding bioimaging applications. Recently, extremely bright molecular crystals of cationic fluorophores were obtained by hierarchical coassembly with cyanostar anion-receptor complexes. These small-molecule ionic isolation lattices (SMILES) ensure spatial and electronic isolation to prohibit aggregation quenching of dyes. We report a simple, one-step supramolecular approach to formulate SMILES materials into NPs. Rhodamine-based SMILES NPs stabilized by glycol amphiphiles show high fluorescence quantum yield (30 %) and brightness per volume (5000 M-1 cm(-1)/nm(3)) with 400 dye molecules packed into 16-nm particles, corresponding to a particle absorption coefficient of 4x10(7) M-1 cm(-1). UV excitation of the cyanostar component leads to higher brightness (>6000 M-1 cm(-1)/ nm(3)) by energy transfer to rhodamine emitters. Coated NPs stain cells and are thus promising for bioimaging.

KW - cell imaging

KW - cyanostar macrocycles

KW - fluorescent dyes

KW - fluorescent nanoparticles

KW - SMILES

U2 - 10.1002/anie.202100950

DO - 10.1002/anie.202100950

M3 - Journal article

C2 - 33577094

VL - 60

SP - 9450

EP - 9458

JO - Angewandte Chemie International Edition

JF - Angewandte Chemie International Edition

SN - 1433-7851

IS - 17

ER -

ID: 286626492